October 8, 2021

VIA EDGAR

Securities and Exchange Commission

Division of Corporation Finance

100 F. Street, N.E.

Washington, D.C. 20549

 

 

 

Re: XORTX Therapeutics Inc. (the "Company")

Registration Statement on Form F-1

File No. 333-258741

 

Ladies and Gentlemen:

 

In accordance with Rule 461 under the Securities Act of 1933, as amended, the undersigned respectfully requests that the effective date of the above-referenced Registration Statement be accelerated so that the same will become effective at 4:30PM on October 12, 2021, or as soon thereafter as is practicable, unless we or our outside counsel, Dorsey & Whitney LLP, request by telephone that such Registration Statement be declared effective at some other time.

 

  Very truly yours,
   
  XORTX Therapeutics Inc.
     
  By: /s/ Allen Davidoff
     
  Name: Allen Davidoff
   
  Title: Chief Executive Officer